IL-33/ST2 induces neutrophil-dependent reactive oxygen species production and mediates gout pain
نویسندگان
چکیده
منابع مشابه
Reactive oxygen species-dependent nitric oxide production
Running head: 1 Hydrogen, stomatal closure and drought tolerance 2 3 Authors: 4 Yanjie Xie, Yu Mao, Wei Zhang, Diwen Lai, Qingya Wang, Wenbiao Shen 5 6 Address: 7 1 College of Life Sciences, Nanjing Agricultural University, Nanjing 210095, China 8 2 Laboratory Center of Life Sciences, Nanjing Agricultural University, Nanjing 9 210095, China 10 11 *Corresponding author 12 Wenbiao Shen 13 College...
متن کاملNADPH Oxidase-Dependent Production of Reactive Oxygen Species Induces Endoplasmatic Reticulum Stress in Neutrophil-Like HL60 Cells
Reactive oxygen species (ROS) primarily produced via NADPH oxidase play an important role for killing microorganisms in neutrophils. In this study we examined if ROS production in Human promyelocytic leukemia cells (HL60) differentiated into neutrophil-like cells (dHL60) induces ER stress and activates the unfolded protein response (UPR). To cause ROS production cells were treated with PMA or b...
متن کاملDrp1-dependent mitochondrial fission mediates osteogenic dysfunction in inflammation through elevated production of reactive oxygen species
Although previous studies have implicated pro-inflammatory cytokines, such as tumor necrosis factor-α (TNF-α) and interleukin-6 (IL-6), to be detrimental for osteogenic activity, the related regulatory mechanisms are not yet fully validated. Since mitochondria host several essential metabolic processes and play a pivotal role in cellular functions, whether and how mitochondrial function contrib...
متن کاملAdipocyte Reactive Oxygen Species Production
SUN, XIAOCUN AND MICHAEL B. ZEMEL. 1 ,25Dihydroxyvitamin D3 modulation of adipocyte reactive oxygen species production. Obesity. 2007;15:1944–1953. Objective: We have previously shown 1 ,25-dihydroxyvitamin D3 [1 ,25-(OH)2D3] to inhibit mitochondrial uncoupling protein 2 (UCP2) expression in adipocytes and that in vivo suppression of calcitriol levels with calcium-rich diets increases UCP2 expr...
متن کاملO 22: Reactive Oxygen Species and Epilepsy
Seizure activity has been proposed to result in the generation of reactive oxygen species (ROS), which then contribute to seizure-induced neuronal damage and eventually cell death. Although the mechanisms of seizure-induced ROS generation are unclear, mitochondria and cellular calcium overload have been proposed to have a crucial role. We aim to determine the sources of seizure-induced ROS and ...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Theranostics
سال: 2020
ISSN: 1838-7640
DOI: 10.7150/thno.48028